TB-500

Signalling & repair

Synthetic fragment of a natural protein, researched in muscle and tissue regeneration.

Purity	≥99%
Molecular formula	C₅₀H₈₉N₁₅O₁₅
Molecular weight	1164.30 Da
CAS number	885340-08-9

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10 mg 64.95€

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It arrives lyophilized: you need bacteriostatic water to reconstitute it.

Bacteriostatic water · 10 ml 9.95 €

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Below that: 7,99 € to Spain · 12,99 € to the rest of the EU

For scientific research only. This product is not approved for human, veterinary or diagnostic use. By purchasing it you confirm that you will use it exclusively for laboratory research purposes.

Research background

TB-500 is the synthetic version of the active fragment of thymosin beta-4, a 43 amino acid protein present in almost every tissue. The fragment corresponds to the actin-binding region, where much of its biological activity resides.

What is being investigated revolves around cytoskeletal dynamics: thymosin beta-4 sequesters monomeric actin and thereby influences cell migration, a step required both in tissue repair and in the formation of new blood vessels. There is work in models of cardiac, corneal and skin injury, all of it preclinical or in early clinical phases.

Read the scientific page on TB-500

Reconstitution and handling

Work on a clean surface and disinfect the vial stopper with an alcohol wipe before piercing it.
Add the bacteriostatic water slowly, letting it run down the inner wall of the vial rather than landing on the powder.
Do not shake. Swirl the vial gently until the lyophilized powder has fully dissolved: vigorous agitation degrades the peptide.
The solution should come out clear. If it turns cloudy or shows suspended particles, do not use it.